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The Anti-Inflammatory Diet & Action Plans: 4-Week Meal Plans to Heal the Immune System and Restore Overall Health

Culturelle(R) Debuts Only Triple-Action Immune Boosting Supplement to Include Probiotics

By Marketwired .	Article Rating:
August 24, 2015 10:22 AM EDT

CROMWELL, CT–(Marketwired – August 24, 2015) – A leading immune health probiotic brand is bringing new innovation to the cough/cold aisle this month. Culturelle Advanced Immune Defense is the first supplement with a triple action immune boosting formula strengthened by probiotics.* The product is now available on shelves at drug, grocery and mass retailers nationwide.

The new formula is comprised of clinically proven ingredients for immune protection including: EpiCor®, a specialized yeast fermentate, Lactobacillus GG, the number one studied probiotic strain backed by over 125 studies focusing on immune health; and Vitamin C and Zinc.*††

“Over 70 percent of your immune system is in your digestive tract, so a healthy and balanced digestive system plays a vital role in maintaining your overall health and well-being,” says Dr. Jennifer Wider^, health expert and medical advisor. “By adding the probiotic to Advanced Immune Defense, Culturelle is offering users the benefit of a clinically proven probiotic††, in combination with the antioxidant action in EpiCor and Vitamin C, giving your immune system an extra boost.”*

“As the number one probiotic brand^^, our goal is to provide Culturelle users the most effective supplement to give their immune system extra protection*,” says Sara Urbanek, Culturelle brand manager at i-Health, Inc. “New Advanced Immune Defense adds innovation by going beyond the typical Vitamin C and Zinc, giving consumers the clinically proven ingredients; Lactobacillus GG†† and antioxidant benefit of EpiCor®, which will provide a level of advanced immune health protection never seen before in this category.”

Each once-a-day serving of Culturelle Advanced Immune Defense comes in a capsule-in-capsule form — a technology that ensures freshness and viability of the probiotic — for easy usage with no need to add water.

Culturelle Advanced Immune Defense is available in the cough/cold aisle at all major food and drug retailers nationwide, including Walmart, Target, CVS, Walgreens and Rite-Aid.

To learn more about this product and receive a $2.00 coupon, visit www.culturelle.com.

About Culturelle® Probiotics
Culturelle® is a leading national probiotic brand focused on improving the digestive and immune health of American families. Its portfolio of products covers the needs of families from children to adults. It is the only probiotic supplement brand in the U.S. to contain 100% Lactobacillus GG, the most clinically studied probiotic strain†† which has been demonstrated to restore the natural balance of good bacteria in the digestive tract to help alleviate occasional digestive distress as well as support the body’s own natural defenses.*

About EpiCor®
Produced by a proprietary fermentation process, EpiCor is a unique dietary ingredient made with Saccharomyces cerevisiaeand consists of beneficial vitamins, minerals, amino acids and antioxidants. More than just an immune booster, the science surrounding EpiCor shows that EpiCor helps to maintain a strong immune system to support year-round good immune health.* EpiCor is not an isolated compound, as are many immune support ingredients on the market, but a complex comprised of beneficial metabolites together with vitamins, minerals, amino acids and antioxidants working together to support immune health.*

Culturelle® used under license by i-Health, Inc.

EpiCor® is a registered trademark of Embria Health Sciences, LLC.

^ Dr.Wider is a paid spokesperson for Culturelle.

^ ^ Nielsen xAOC 52 Weeks unit/dollar sales ending July 11, 2015

†† Based on the number of Lactobacillus GG clinical studies, as of May, 2015

± Sourced from Vitamin C and EpiCor®

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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Culturelle(R) Debuts Only Triple-Action Immune Boosting Supplement to Include Probiotics

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How the Immune System Promotes Digestive Health

As many as 1.4 million Americans suffer from uncomfortable abdominal cramping and diarrhea that come with ulcerative colitis and Crohn’s disease. These conditions, collectively known as inflammatory bowel disease (IBD), are associated with an imbalance among the thousands of species of “good” bacteria that inhabit the gut. A University of Utah study published in Cell Host and Microbe demonstrates that mice deficient for a component of the immune system, a protein called MyD88, have an imbalanced gut bacterial community – with some species dominating over others – and are more susceptible to contracting a severe IBD-like illness. Further, fecal transplants from healthy donors alleviate IBD symptoms in these mice.

The results show that the immune system encourages growth of a healthy community of “good” bacteria that is important for digestive health. This perspective on immune system function is in contrast to it’s best known role as the first line of defense in the fight against pathogens, including invasive bacteria.

“Our work highlights that the immune system shapes the composition of bacterial communities in the intestine,” said senior author June Round, Ph.D., assistant professor of pathology at the University of Utah School of Medicine. “This interaction is important because it’s becoming more and more clear that resident microbes are very important for our health.”

Considering that some people with IBD have mutations in genes that are part of a MyD88-controlled pathway, fecal transplantation – which involves collecting and processing stool from a healthy donor, and delivering it into a recipient’s gut – might help to ameliorate disease in these people, according to Round.

Loss of MyD88 disturbs the microbial community because it disrupts production of IgA. This class of antibody works like a gatekeeper that controls which types of bacteria, and how many, are allowed to inhabit the gut. By performing inventories of total gut bacteria compared to species that bind IgA, the scientists determined that without MyD88, IgA failed to recognize species that it can otherwise.

The work not only demonstrates that a balanced microbial community promotes digestive health, but that it also shapes the host’s immune system. Mice raised in a sterile, germ-free environment have a faulty immune system, a defect that can be fixed if they are fed bacterial components, TLR2 agonists, that activates the immune system. The rescue does not work in mice deficient for MyD88, demonstrating again that the protein is key to interpreting communications between microbes and the immune system.

“There is a conversation between our immune system and our resident bacteria,” explains Round. “The microbes can send signals that tell our immune system how to develop and in turn our immune system can shape what types of microbes live on our body.”

The dependency of host health on good bacteria has made the conversation a necessity. In response to demand, the immune system has adapted from a system designed to fight the body’s invaders to one that also nurtures a harmonious relationship with the body’s peaceful inhabitants.

Source: University of Utah

How the Immune System Promotes Digestive Health